Functional amalysis of Vc-Mrp and Vc-NhaP1, two non-canonical Na+/H+ antiporters in vibrio cholerae
Functional amalysis of Vc-Mrp and Vc-NhaP1, two non-canonical Na+/H+ antiporters in vibrio cholerae
批准号:
227414-2009
负责人:
Dibrov, Pavel
金额:
$2.55万
依托单位:
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2011
资助国家:
加拿大
项目状态:
已结题
起止时间:
2011-01-01 至 2012-12-31
中文摘要
霍乱弧菌引起的霍乱往往是致命的疾病,霍乱有着漫长而严峻的历史,目前仍影响着数百万人,主要是在亚洲、非洲和拉丁美洲的发展中国家。在这种危险的人类病原体中,钠的循环与毒力密切相关。因此,对该菌体内钠循环的研究具有重要的科学意义和医学意义。霍乱弧菌的钠循环依赖于称为Na+/H+逆向转运蛋白的特定蛋白质。这些抗转运蛋白通常是单膜蛋白,从细胞中清除有毒的钠离子,以换取外部质子。
英文摘要
Vibrio cholerae causes the often-fatal disease cholera, which has a long grim history and still affects many millions of people, mostly in the developing countries of Asia, Africa and Latin America. In this dangerous human pathogen, the circulation of sodium is intimately related to virulence. Therefore, investigation of sodium circulation in this bacterium is very important from both scientific and medical point of view. The sodium circulation in V. cholerae relies on specific proteins called Na+/H+ antiporters. These antiporters are usually single membrane proteins removing toxic sodium ions from the cell in exchange for external protons.
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会议论文
Structure, function and dynamics of the cation-proton antiporter Vc-NhaP2 in Vibrio cholerae
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批准号:RGPIN-2019-05481
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.33万
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财政年份:2022
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负责人:Dibrov, Pavel
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依托单位:
Structure, function and dynamics of the cation-proton antiporter Vc-NhaP2 in Vibrio cholerae
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批准号:RGPIN-2019-05481
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.33万
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财政年份:2021
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负责人:Dibrov, Pavel
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依托单位:
Structure, function and dynamics of the cation-proton antiporter Vc-NhaP2 in Vibrio cholerae
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批准号:RGPIN-2019-05481
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.33万
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财政年份:2020
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负责人:Dibrov, Pavel
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依托单位:
Structure, function and dynamics of the cation-proton antiporter Vc-NhaP2 in Vibrio cholerae
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批准号:RGPIN-2019-05481
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.33万
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财政年份:2019
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负责人:Dibrov, Pavel
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依托单位:
Comparative analysis of cation-proton antiporters of NhaP type in Vibrio cholerae and Yersinia pestis
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批准号:227414-2012
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.48万
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财政年份:2016
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负责人:Dibrov, Pavel
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依托单位:
Comparative analysis of cation-proton antiporters of NhaP type in Vibrio cholerae and Yersinia pestis
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批准号:227414-2012
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.48万
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财政年份:2015
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负责人:Dibrov, Pavel
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依托单位:
Comparative analysis of cation-proton antiporters of NhaP type in Vibrio cholerae and Yersinia pestis
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批准号:227414-2012
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.48万
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财政年份:2014
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负责人:Dibrov, Pavel
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依托单位:
Comparative analysis of cation-proton antiporters of NhaP type in Vibrio cholerae and Yersinia pestis
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批准号:227414-2012
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.48万
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财政年份:2013
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负责人:Dibrov, Pavel
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依托单位:
Comparative analysis of cation-proton antiporters of NhaP type in Vibrio cholerae and Yersinia pestis
-
批准号:227414-2012
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$2.48万
-
财政年份:2012
-
负责人:Dibrov, Pavel
-
依托单位:
Functional amalysis of Vc-Mrp and Vc-NhaP1, two non-canonical Na+/H+ antiporters in vibrio cholerae
-
批准号:227414-2009
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.55万
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财政年份:2010
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负责人:Dibrov, Pavel
-
依托单位:
Functional amalysis of Vc-Mrp and Vc-NhaP1, two non-canonical Na+/H+ antiporters in vibrio cholerae
-
批准号:227414-2009
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$2.55万
-
财政年份:2009
-
负责人:Dibrov, Pavel
-
依托单位:
Genetics and biochemistry of Na+/H+ antiport in Vibrio cholerae
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批准号:227414-2004
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.04万
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财政年份:2008
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负责人:Dibrov, Pavel
-
依托单位:
Genetics and biochemistry of Na+/H+ antiport in Vibrio cholerae
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批准号:227414-2004
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项目类别:Discovery Grants Program - Individual
-
资助金额:$2.04万
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财政年份:2007
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负责人:Dibrov, Pavel
-
依托单位:
Genetics and biochemistry of Na+/H+ antiport in Vibrio cholerae
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批准号:227414-2004
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项目类别:Discovery Grants Program - Individual
-
资助金额:$2.04万
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财政年份:2006
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负责人:Dibrov, Pavel
-
依托单位:
Genetics and biochemistry of Na+/H+ antiport in Vibrio cholerae
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批准号:227414-2004
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项目类别:Discovery Grants Program - Individual
-
资助金额:$2.04万
-
财政年份:2005
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负责人:Dibrov, Pavel
-
依托单位:
Genetics and biochemistry of Na+/H+ antiport in Vibrio cholerae
-
批准号:227414-2004
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$2.04万
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财政年份:2004
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负责人:Dibrov, Pavel
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依托单位:
Identification and characterization of novel Na+ exporting proteins in higher plants
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批准号:227414-2000
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.04万
-
财政年份:2003
-
负责人:Dibrov, Pavel
-
依托单位:
Identification and characterization of novel Na+ exporting proteins in higher plants
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批准号:227414-2000
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$2.04万
-
财政年份:2002
-
负责人:Dibrov, Pavel
-
依托单位:
Identification and characterization of novel Na+ exporting proteins in higher plants
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批准号:227414-2000
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$2.04万
-
财政年份:2001
-
负责人:Dibrov, Pavel
-
依托单位:
Identification and characterization of novel Na+ exporting proteins in higher plants
-
批准号:227414-2000
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$2.04万
-
财政年份:2000
-
负责人:Dibrov, Pavel
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依托单位:
海外基金