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Characterization of RND efflux pumps of acinetobacter baumannii

Characterization of RND efflux pumps of acinetobacter baumannii
鲍曼不动杆菌 RND 外排泵的表征
批准号:
355806-2010
负责人:
Kumar, Ayush
金额:
$1.97万
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2011
资助国家:
加拿大
项目状态:
已结题
起止时间:
2011-01-01 至 2012-12-31

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英文摘要
Acinetobacter baumannii is a rod-shaped Gram-negative bacterium that commonly inhabits soil. A. baumannii is highly resistant to various antimicrobials, and multidrug clinical isolates have been isolated all over the world including in Canada. Our hypothesis is that efflux pumps belonging to the Resistance-Nodulation-cell Division (RND) family aid in the survival of A. baumannii in the presence of harmful compounds (including antimicrobials, heavy metals, detergents, and dyes), and that characterization of these efflux pumps will contribute to an understanding of the survival mechanisms employed by this organism. Using powerful molecular and genetic tools, this program will characterize three RND complex-encoding operons,
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Determining physiological role(s) of Resistance-Nodulation-Division efflux pumps of Acinetobacter baumannii
  • 批准号:
    RGPIN-2021-02902
  • 项目类别:
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  • 财政年份:
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Determining physiological role(s) of Resistance-Nodulation-Division efflux pumps of Acinetobacter baumannii
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  • 项目类别:
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  • 资助金额:
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  • 项目类别:
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    2021
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Molecular mechanisms of biocide and antibiotic resistance in Acinetobacter baumannii
  • 批准号:
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  • 财政年份:
    2020
  • 负责人:
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