Model of microcirculation: effect of cell interactions on blood flow

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Microcirculation in the human body, which is composed of numerous vessels with diameters less than 50 micrometers, is the main exchange site between blood and tissues. Knowledge of microcirculation is essential to understanding numerous pathologies and testing therapeutic solutions. The behaviour of blood in microcirculation is very complex because it cannot be considered as a liquid, but rather as a collection of interacting particles. Red blood cell circulation and interaction in micro-vessels is of great interest. Moreover, red blood cells may adversely affect blood behaviour, and as a consequence, blood flow if they are too abundant, less deformable or if they tend to aggregate abnormally.