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Role of Oxygen as a Regulator of Tumour Cell Plasticity and Metastatic Potential

Role of Oxygen as a Regulator of Tumour Cell Plasticity and Metastatic Potential
氧作为肿瘤细胞可塑性和转移潜能调节剂的作用
批准号:
185428
负责人:
Postovit Lynne-Marie
金额:
$18.21万
依托单位国家:
加拿大
项目类别:
Salary Programs
财政年份:
2008
资助国家:
加拿大
项目状态:
已结题
起止时间:
2008-09-01 至 2011-09-01

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中文摘要
翻译
快速生长的肿瘤包含许多低氧(缺氧)区域,这些缺氧区域的存在与癌症转移和不良临床结果相关。 以类似于干细胞的方式,侵袭性癌细胞的亚群
英文摘要
Rapidly growing tumours contain many areas of low oxygen (hypoxia), and the presence of these hypoxic regions is associated with cancer metastasis and a poor clinical outcome. In a manner similar to stem cells, sub-populations of aggressive cancer cells
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