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Elucidating the Role of Connective Tissue Growth Factor in Intervertebral Disc Development, Health and Disease

Elucidating the Role of Connective Tissue Growth Factor in Intervertebral Disc Development, Health and Disease
阐明结缔组织生长因子在椎间盘发育、健康和疾病中的作用
批准号：
239212
负责人：
Sguin Cheryle A
金额：
$42.0万
依托单位：
University of Western Ontario
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2011
资助国家：
加拿大
项目状态：
已结题
起止时间：
2011-09-01 至 2016-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=239212&lang=en
关键词：
Connective Tissue Growth Factor Disc Aging/Degeneration Disc Development Extracellular Matrix Intervertebral Disc Notochord Cells Spine Tissue Specific Gene Knockout

项目摘要

项目成果

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Low back pain as a result of intervertebral disc (IVD) degeneration is a cause of major disability and constitutes the leading musculoskeletal disorder responsible for days lost from work. Studies show that chronic back pain is increasing at an alarming r
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