Disc degeneration, back pain and obesity: PPARdelta as a potential therapeutic target

椎间盘退变、背痛和肥胖：PPARδ 作为潜在的治疗靶点

• 批准号: 408543
• 负责人: Sguin Cheryle A
• 金额: $ 40.68万
• 依托单位: University of Western Ontario
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2019
• 资助国家: 加拿大
• 起止时间: 2019-09-01 至 2024-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=408543&lang=en
• 关键词: Back Pain; Behavioral Analysis Of Pain; Cell Biology; Disc Degeneration; Genetically Modified Mouse Models; Intervertebral Disc; Nuclear Receptors; Obesity; Ppar Delta

Back pain is the most common cause of disability worldwide, affecting over 80% of Canadians. Though the specific causes of back pain are not well understood, it is often associated with degeneration of intervertebral discs, the cartilaginous structures th

背部疼痛是全球最常见的残疾原因，影响着超过80%的加拿大人。尽管背痛的具体原因尚不清楚，但它通常与椎间盘退变有关，软骨结构是腰椎退变的主要原因。