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Studies of the molecular mechanisms by which mutations in the SUR2A NBDs cause cardiovascular diseases

Studies of the molecular mechanisms by which mutations in the SUR2A NBDs cause cardiovascular diseases
SUR2A NBDs突变导致心血管疾病的分子机制研究
批准号：
241284
负责人：
Kanelis Voula
金额：
$21.86万
依托单位：
University of Toronto
依托单位国家：
加拿大
项目类别：
Salary Programs
财政年份：
2011
资助国家：
加拿大
项目状态：
已结题
起止时间：
2011-09-01 至 2016-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=241284&lang=en
关键词：
Abc Transporters Fluorescence Spectroscopy Katp Channels Nmr Spectroscopy Nucleotide Binding Domains Phosphorylation Protein Dynamics Protein Structure Protein-Protein Interactions Sulfonylurea Receptors

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中文摘要
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英文摘要
Potassium ion channels in cells are essential for healthy hearts. These channels are formed from two different types of proteins. One protein, called Kir6.2, forms the channel pore while the other protein, known as SUR2A, regulates opening and closing of
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Studies of the molecular mechanisms by which mutations in the SUR2A NBDs cause cardiovascular diseases
  • 批准号：
    201150
  • 项目类别：
    Operating Grants
  • 资助金额：
    $32.81万
  • 财政年份：
    2010
  • 负责人：
    Kanelis Voula
  • 依托单位：
    University of Toronto
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