The role of DGAT2 in triacylglycerol synthesis and lipid droplet formation

DGAT2 在三酰甘油合成和脂滴形成中的作用

• 批准号: 250502
• 负责人: Stone Scot J
• 金额: $ 7.29万
• 依托单位: University of Saskatchewan
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2011
• 资助国家: 加拿大
• 起止时间: 2011-09-01 至 2012-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=250502&lang=en
• 关键词: Adipocyte; Lipid Biochemistry; Lipid Droplet; Obesity; Proteasome; Protein Interaction; Structure/Function; Subcellular Localization; Triacylglycerol; Ubiquitination

Triacylglycerol (TG) is the major source of stored energy in humans. However, excessive accumulation of TG in tissues can lead to obesity, diabetes and heart disease. Obesity has now reached epidemic proportions in Canada with 25% of the Canadian populati

三酰甘油（TG）是人类储存能量的主要来源。然而，TG在组织中的过度积累可导致肥胖、糖尿病和心脏病。肥胖症在加拿大已经达到了流行病的比例，25%的加拿大人口患有肥胖症。