Imaging transcription factors in living mammalian embryos to reveal cell-to-cell variability

对活体哺乳动物胚胎中的转录因子进行成像以揭示细胞间的变异

• 批准号: DP120104594
• 负责人: Dr Nicolas Plachta
• 金额: $ 17.91万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP120104594
• 关键词: Imaging; transcription; factors; living; mammalian

The mechanisms controlling how single cells activate different genes are typically studied in cells grown in culture dishes. This project will apply novel imaging methods to study how gene regulatory molecules control cells in living mouse embryos.

通常在培养皿中生长的细胞中研究控制单细胞如何激活不同基因的机制。该项目将应用新颖的成像方法来研究基因调控分子如何控制活体小鼠胚胎中的细胞。