Nano-mechanical and nano-structural investigation of dentine: unravelling a novel nano-scale regulator of high durability of mineralised tissues

牙本质的纳米力学和纳米结构研究：揭示矿化组织高耐久性的新型纳米级调节剂

• 批准号: DP120104837
• 负责人: Prof Michael Swain
• 金额: $ 26.52万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP120104837
• 关键词: Nano; mechanical; nano; structural; investigation

This project proposes that proteoglycans (PG) are key regulators of the high durability of dentine. PGs are primarily responsible for the structural organization of collagen in all vertebrates, however virtually nothing is known about their role on the biomechanics of mineralized tissues. This study aims to thoroughly address this question.

该项目提出，蛋白多糖(PG)是牙本质高耐久性的关键调节物质。PGS在所有脊椎动物中主要负责胶原的结构组织，然而对于它们在矿化组织的生物力学中的作用几乎一无所知。本研究旨在彻底解决这一问题。