Pharmacological/nutraceutical rescue of mutated cardiac ion channels to treat inherited cardiac arrhythmias

突变心脏离子通道的药理学/营养疗法治疗遗传性心律失常

• 批准号: 258192
• 负责人: Zhang Shetuan
• 金额: $ 7.29万
• 依托单位: Queen's University (Kingston, Ontario)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2011
• 资助国家: 加拿大
• 起止时间: 2011-10-01 至 2012-10-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=258192&lang=en
• 关键词: Animal Models And Pharmacology; Drugs And Lipids; Ion Channel Expression; Long Qt Syndrome; Molecular Biology; Patch Clamp; Pharmacology Of Ion Channels; Potassium Channels; Rescue Of Ion Channel Trafficking

Background: Long QT syndrome (LQTS) is a cardiac electrical disorder caused by malfunction of ion channels, which can lead to life-threatening dysrhythmias (irregular heartbeats) and unexpected sudden death. LQTS can be inherited due to naturally occurrin

背景资料：长QT综合征（LQTS）是一种由离子通道功能障碍引起的心脏电紊乱，可导致危及生命的心律失常（不规则心跳）和意外猝死。LQTS可以遗传，