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A novel regulation of the hERG channel and its role in long QT syndrome and sudden cardiac death

A novel regulation of the hERG channel and its role in long QT syndrome and sudden cardiac death
hERG 通道的新调节及其在长 QT 综合征和心源性猝死中的作用
批准号：
323132
负责人：
Zhang Shetuan
金额：
$51.96万
依托单位：
Queen's University (Kingston, Ontario)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2015
资助国家：
加拿大
项目状态：
已结题
起止时间：
2015-03-01 至 2020-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=323132&lang=en
关键词：
Animal Models Cardiac Arrhythmias Cardiac Electrophysiology Cardiac Ischemia Herg Hypokalemia Ion Channels Molecular Biology Patch Clamp Protease Activities

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英文摘要
Background: The cardiac electricity-generating protein, named "HERG", is important for normal heart rhythm. A reduction in the amount of HERG protein disturbs heart rhythm and causes sudden death. Diseased conditions such as insufficient blood supply to
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