Synthetic Toll-like Receptor 4 Agonists as Potential Adjuvants for Use in Animal Vaccines
Synthetic Toll-like Receptor 4 Agonists as Potential Adjuvants for Use in Animal Vaccines
批准号:
428767-2011
负责人:
Jiang, ZiHua
金额:
$1.82万
依托单位:
依托单位国家:
加拿大
项目类别:
Engage Grants Program
财政年份:
2011
资助国家:
加拿大
项目状态:
已结题
起止时间:
2011-01-01 至 2012-12-31
中文摘要
佐剂在开发新的疫苗以对抗同伴动物和家畜中危及生命的疾病方面发挥着至关重要的作用。疫苗保护在农业中是一个特别令人担忧的问题,因为农业依赖于维持畜群动物的健康。随着新型佐剂的开发,对现有动物疫苗的改进也可能增加它们的安全性和有效性。目前用于动物疫苗的佐剂很少,因此迫切需要开发和鉴定新的佐剂。
英文摘要
Adjuvants play an essential role in the development of new vaccines to combat life-threatening diseases in companion animals as well as livestock. Vaccine protection is a particular concern in agriculture where farming depends on maintaining health in herd animals. Improvement of existing animal vaccines with the development of novel adjuvants could also potentially increase their safety and efficacy. Currently there are only a few adjuvants available for vaccines in animal use, and therefore there is an urgent need to develop and characterize new adjuvants.
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