The Genomics and Proteomics of TMEM43, its association with Arrythmogenic Right Ventricular Cardiomyopathy and the translation of this knowledge to improve the health care of those affected.

TMEM43 的基因组学和蛋白质组学、其与致心律失常性右室心肌病的关联以及这些知识的转化以改善受影响者的医疗保健。

• 批准号: 174406
• 负责人: Young Terry-Lynn
• 金额: --
• 依托单位: Memorial University of Newfoundland
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2008
• 资助国家: 加拿大
• 起止时间: 2008-10-01 至 2009-10-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=174406&lang=en
• 关键词: Animal Model Mechanisms; Arrythmogenic Right Ventricular Cardiomyopathy; Ge3ls; Proteins; Tmem43; Translational Research

The application represents a unique opportunity to capitalize on a Canadian discovery of the TMEM43 gene causing an autosomal dominant form of sudden cardiac death in 15 multiplex ARVC (Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia type-5) fam

该申请代表了一个独特的机会，利用加拿大发现的TMEM 43基因，该基因导致15个多发性ARVC（致心律失常性右心室心肌病/发育不良5型）家族的常染色体显性形式的心脏性猝死。