Improving Muscular Dystrophy Cell Therapy with Drug-Related Gene Knock-Down in Donor Cells

通过敲低供体细胞中的药物相关基因改善肌营养不良症细胞治疗

• 批准号: 251801
• 负责人: Antoun Alen
• 金额: $ 0.36万
• 依托单位: University of Ottawa
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2012
• 资助国家: 加拿大
• 起止时间: 2012-01-01 至 2012-04-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=251801&lang=en
• 关键词: Cell Therapy; Drug-Regulated Gene Knock-Down; Duchenne Muscular Dystrophy; Immunostaining; Lentivirus; Satellite Cells; Shrna; Six1

Duchenne Muscular Dystrophy (DMD) is a genetic disorder characterized by the gradual weakening and deterioration of muscles in an individual. This problem is due to the absence of production of a specific protein, dystrophin. There is currently no therapy

杜氏肌营养不良症（DMD）是一种遗传性疾病，其特征是个体肌肉逐渐减弱和退化。这个问题是由于缺乏生产的特定蛋白质，肌营养不良蛋白。目前没有治疗方法