An Accelerated Solvent Extraction System for the Laboratory for the Analysis of Natural and Synthetic Environmental Toxicants (LANSET).

用于天然和合成环境毒物分析实验室的加速溶剂萃取系统 (LANSET)。

• 批准号: 440450-2013
• 负责人: Blais, Jules
• 金额: $ 6.3万
• 依托单位: University of Ottawa
• 依托单位国家: 加拿大
• 项目类别: Research Tools and Instruments - Category 1 (<$150,000)
• 财政年份: 2012
• 资助国家: 加拿大
• 起止时间: 2012-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=507540
• 关键词: Accelerated; Solvent; Extraction; System; Laboratory

The Laboratory for the Analysis of Natural and Synthetic Environmental Toxicants (LANSET) is a research and training facility at the University of Ottawa that routinely analyzes a wide range of natural and synthetic environmental toxicants for the broader research community at the University of Ottawa and elsewhere. The analytical methodologies applied at LANSET mainly include the analysis of plant extracts and environmental samples by various chromatographic and spectrometric methods. Our natural product and environmental toxicology studies rely on samples processed with an Accelerated Solvent Extraction (ASE) system. The ASE allows for the rapid, and highly efficient extraction of a wide suite of molecules from a variety of sample types. In addition the instrument is a key step for metabolite profiling and quantification of known compounds and we have published several validated methods to optimize extraction of environmental samples. Using the ASE, we can analyze environmental samples for synthetic pollutants (with validated methods for pharmaceuticals, personal care products, steroidal estrogens, polyaromatic hydrocarbons, and others), and algal toxins (microcystins, anatoxins, nodularin).

天然和合成环境毒物分析实验室 (LANSET) 是渥太华大学的一个研究和培训机构，为渥太华大学和其他地方的更广泛的研究界定期分析各种天然和合成环境毒物。 LANSET应用的分析方法主要包括通过各种色谱和光谱方法对植物提取物和环境样品进行分析。我们的天然产品和环境毒理学研究依赖于使用加速溶剂萃取 (ASE) 系统处理的样品。 ASE 可以从各种样品类型中快速、高效地提取多种分子。此外，该仪器是已知化合物代谢物分析和定量的关键步骤，我们已经发布了几种经过验证的方法来优化环境样品的提取。使用 ASE，我们可以分析环境样品中的合成污染物（采用针对药物、个人护理产品、类固醇雌激素、多环芳烃等的经过验证的方法）和藻类毒素（微囊藻毒素、鱼毒素、球藻毒素）。