MicroRNA misregulation in Multiple Sclerosis - impacts on oligodendrocytes and their ability to differentiate, mature and myelinate axons in the central nervous system.

多发性硬化症中的 MicroRNA 失调 - 影响少突胶质细胞及其在中枢神经系统中分化、成熟和髓鞘化轴突的能力。

• 批准号: 253396
• 负责人: Kornfeld Samantha
• 金额: $ 1.27万
• 依托单位: Ottawa Hospital Research Institute
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2012
• 资助国家: 加拿大
• 起止时间: 2012-02-01 至 2013-02-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=253396&lang=en
• 关键词: Experimental Autoimmune Encephalitis; Lentiviral Microrna Expression Vectors; Microrna; Multiple Sclerosis; Oligodendrocytes; Stem-Loop Qrt-Pcr; Tissue Culture

MicroRNAs are small regulatory molecules that control gene expression. Mammalian systems use them to regulate important aspects of growth, development, tissue differentiation and cell survival throughout the life of an organism. Because of the significanc

MicroRNA是控制基因表达的小调节分子。哺乳动物系统使用它们来调节生物体整个生命中的生长、发育、组织分化和细胞存活的重要方面。由于其重要性，