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Misregulation of microRNAs in multiple sclerosis - impacts on oligodendrocytes and their ability to differentiate, mature and myelinate axons in the central nervous system

Misregulation of microRNAs in multiple sclerosis - impacts on oligodendrocytes and their ability to differentiate, mature and myelinate axons in the central nervous system
多发性硬化症中 microRNA 的失调 - 对少突胶质细胞及其在中枢神经系统中分化、成熟和髓鞘化轴突的能力的影响
批准号：
283945
负责人：
Kornfeld Samantha
金额：
$7.65万
依托单位：
Ottawa Hospital Research Institute
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2012
资助国家：
加拿大
项目状态：
已结题
起止时间：
2012-10-01 至 2015-10-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=283945&lang=en
关键词：
Cytoskeletal Organization Experimental Autoimmune Encephalitis Lentiviral Transduction Microrna Multiple Sclerosis Oligodendrocytes Remyelination Stem-Loop Qpcr

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英文摘要
MicroRNAs are small regulatory molecules that control gene expression. Mammalian systems use them to regulate important aspects of growth, development, tissue differentiation and cell survival throughout the life of an organism. Because of the significanc
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MicroRNA misregulation in Multiple Sclerosis - impacts on oligodendrocytes and their ability to differentiate, mature and myelinate axons in the central nervous system.
  • 批准号：
    253396
  • 项目类别：
    Studentship Programs
  • 资助金额：
    $1.27万
  • 财政年份：
    2012
  • 负责人：
    Kornfeld Samantha
  • 依托单位：
    Ottawa Hospital Research Institute
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