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Optimization of the antidepressant action of ketamine in treatment-resistant depression and investigations on it's mechanism of action

Optimization of the antidepressant action of ketamine in treatment-resistant depression and investigations on it's mechanism of action
氯胺酮治疗难治性抑郁症的抗抑郁作用优化及作用机制研究
批准号：
254197
负责人：
Blier Pierre
金额：
$32.46万
依托单位：
University of Ottawa Institute of Mental Health Research
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2012
资助国家：
加拿大
项目状态：
已结题
起止时间：
2012-03-01 至 2015-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=254197&lang=en
关键词：
Antidepressant Clinical Trials Depression Glutamate Glutamatergic System Ketamine Major Depression Mood Disorders Nmda Antagonist Treatment Resistant

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中文摘要
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英文摘要
Depression carries the largest burden of all medical disorders in middle to high income countries, as determined by the World Health Organization. Despite many antidepressant strategies, only a third of patients get well after their first treatment and a
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Mechanisms involved in triggering the rapid and sustained antidepressant effects of ketamine
CANADA RESEARCH CHAIRHOLDER / TITULAIRE DE CHAIRE DE RECHERCHE DU CANADA
  • 批准号：
    241522
  • 项目类别：
  • 资助金额：
    $101.99万
  • 财政年份：
    2010
  • 负责人：
    Blier Pierre
  • 依托单位：
    University of Ottawa
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