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Structure function analysis of the dual protein kinase-RNase signaling proteins and the eIF2a protein kinases

Structure function analysis of the dual protein kinase-RNase signaling proteins and the eIF2a protein kinases
双蛋白激酶-RNase 信号蛋白和 eIF2a 蛋白激酶的结构功能分析
批准号:
252331
负责人:
Sicheri Frank
金额:
$81.79万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2012
资助国家:
加拿大
项目状态:
已结题
起止时间:
2012-03-01 至 2017-03-01

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中文摘要
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英文摘要
Ire1 and RNaseL are protein kinases with the unique ability to cleave RNA. The two proteins function in very different cellular processes owing in large part to difference in their ability to recognize and cleave messenger RNA targets. RNaseL plays a key
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The structural biology of the RAF kinase family in RAS-ERK pathway signaling
  • 批准号:
    468744
  • 项目类别:
    Operating Grants
  • 资助金额:
    $78.86万
  • 财政年份:
    2022
  • 负责人:
    Sicheri Frank
  • 依托单位:
Structure-function analysis of the eukaryotic protein kinases Bud32 and Aurora A and their roles in tRNA modification and mitotic entry
  • 批准号:
    443402
  • 项目类别:
    Operating Grants
  • 资助金额:
    $80.81万
  • 财政年份:
    2021
  • 负责人:
    Sicheri Frank
  • 依托单位:
Induced proximity therapeutics for the difficult-to-drug RAS and RAF oncoproteins
  • 批准号:
    452119
  • 项目类别:
    Operating Grants
  • 资助金额:
    $94.77万
  • 财政年份:
    2021
  • 负责人:
    Sicheri Frank
  • 依托单位:
CRC Tier 1
  • 批准号:
    364796
  • 项目类别:
  • 资助金额:
    $101.99万
  • 财政年份:
    2016
  • 负责人:
    Sicheri Frank
  • 依托单位:
海外基金