Organotransition metal chemistry and catalysis

有机过渡金属化学与催化

• 批准号: 4732-2011
• 负责人: Baird, Michael
• 金额: $ 4.01万
• 依托单位: Queen's University
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2012
• 资助国家: 加拿大
• 起止时间: 2012-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=513179
• 关键词: Organotransition; metal; chemistry; catalysis

Organotransition metal chemistry has under gone enormous growth in recent years, with many new compounds being reported in addition to numerous applications to a variety of fields such as organic synthesis, catalysis and materials science. Our research in the recent funding cycle has involved topics as diverse as the synthesis of new compounds which have never previously seen the light of day, catalytic alkene polymerization to give new materials with potentially very useful properties and, in collaboration with scientists in the Cancer Reseach Labs at Queen's, utilization of organometallic compounds as anti-cancer drugs. In the next few years, our research will again involve the synthesis of compounds never previously prepared, as well as studies of their potential applications as interesting new catalysts. We shall also discover new catalysts for effecting novel organic syntheses, and we shall utilize low temperature nuclear magnetic resonance spectroscopy to detect reactive intermediates in important catalytic reactions.

有机过渡金属化学近年来得到了巨大的发展，除了在有机合成、催化和材料科学等领域的大量应用外，还报道了许多新化合物。我们在最近的资助周期中的研究涉及多种主题，如合成以前从未见过的新化合物，催化烯烃聚合以获得具有潜在非常有用特性的新材料，以及与皇后癌症研究实验室的科学家合作，利用有机金属化合物作为抗癌药物。在接下来的几年里，我们的研究将再次涉及以前从未制备过的化合物的合成，以及研究它们作为有趣的新催化剂的潜在应用。我们还将发现新的催化剂，以实现新的有机合成，我们将利用低温核磁共振光谱检测在重要的催化反应的活性中间体。