Structure and Function of Membrane-Associated Peptides and Proteins

膜相关肽和蛋白质的结构和功能

• 批准号: 240795-2012
• 负责人: Straus, Suzana
• 金额: $ 4.01万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2012
• 资助国家: 加拿大
• 起止时间: 2012-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=514455
• 关键词: Structure; Function; Membrane; Associated; Peptides

Every cell is enveloped by a membrane, as are the various compartments within it. Therefore most biological processes either occur at or require transit through a membrane. Indeed, ca. 33% of all proteins are membrane associated. Despite their importance, however, relatively little is known about the 3D architecture of membrane proteins. Knowledge of protein structure is needed to understand function.

每一个细胞都被膜包裹着，就像它里面的各个隔间一样。因此，大多数生物过程要么发生在膜上，要么需要穿过膜。事实上，CA。33%的蛋白质是膜相关的。然而，尽管它们很重要，但对膜蛋白的3D结构知之甚少。了解蛋白质的结构是理解其功能的必要条件。