Regulation of Skeletal Muscle Stem Cell Activity by microRNA and Cytoplasmic mRNP Granules

microRNA 和细胞质 mRNA 颗粒对骨骼肌干细胞活性的调节

• 批准号: 266392
• 负责人: Crist Colin
• 金额: $ 46.62万
• 依托单位: Lady Davis Institute for Medical Research (Mtl)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2012
• 资助国家: 加拿大
• 起止时间: 2012-09-01 至 2017-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=266392&lang=en
• 关键词: Genetics; Microrna; Muscular Dystrophy; Regeneration; Satellite Cell; Skeletal Muscle; Stem Cell

Muscular dystrophies are a group of neuromuscular disorders that are characterized by progressive weakness and wasting of muscles, impeding the ability to walk, speak and ultimately breathe. There is currently no cure. Duchenne muscular dystrophy is the

肌营养不良是一组神经肌肉疾病，其特征在于肌肉的进行性虚弱和消耗，阻碍行走，说话和最终呼吸的能力。目前没有治愈方法。 杜氏肌营养不良症是