A GPR116-(beta)-arrestin1 Signaling Cascade Maintains the Muscle Stem Cell Pool Required for Skeletal Muscle Regeneration

GPR116-(beta)-arrestin1 信号级联维持骨骼肌再生所需的肌肉干细胞库

• 批准号: 461254
• 负责人: Crist Colin
• 金额: $ 50.16万
• 依托单位: Lady Davis Institute for Medical Research (Mtl)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-03-01 至 2027-03-01
• 项目状态: 未结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=461254&lang=en
• 关键词: Adhesion Gpcr; B-Arrestin1; Duchenne Muscular Dystrophy; G-Protein Coupled Receptor (Gpcr); Genetics; Muscle Regeneration; Muscle Stem Cell; Satellite Cell

Regenerative medicine is a branch of translational research aiming to replace, engineer or regenerate human cells, tissues and organs to re-establish normal function. Since this entire process occurs naturally during the repair of tissues by the activatio

再生医学是转化研究的一个分支，旨在替换、改造或再生人体细胞、组织和器官，以重建正常功能。由于这整个过程是在激活修复组织的过程中自然发生的，