The role of Isocitrate Dehydrogenase 1 mutations in tumorigenesis
The role of Isocitrate Dehydrogenase 1 mutations in tumorigenesis
批准号:
268063
负责人:
Mak Tak W
金额:
$55.27万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2012
资助国家:
加拿大
项目状态:
已结题
起止时间:
2012-09-01 至 2017-09-01
中文摘要
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英文摘要
Cancers are defined by their tissue of origin and arise as the result of a series of mutations that lead to tumor progression. Specific mutations in the isocitrate dehydrogenase 1 (IDH1) enzyme, an enzyme that normally functions as a part of a cell's cent
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