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Deciphering the Role of UBR1 E3 Ubiquitin Ligase using a C. elegans Model

Deciphering the Role of UBR1 E3 Ubiquitin Ligase using a C. elegans Model
使用线虫模型解读 UBR1 E3 泛素连接酶的作用
批准号:
267312
负责人:
Zhen Mei
金额:
$38.04万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2012
资助国家:
加拿大
项目状态:
已结题
起止时间:
2012-09-01 至 2017-09-01

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中文摘要
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英文摘要
In humans, mutations in a gene UBR1 lead to the Johanson-Blizzard Syndrome, a congenital disorder with hallmark features in mental retardation and pancreatic exocrine insufficiency. UBR1 encodes an enzyme that targets other proteins for degradation. In th
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Canada Research Chair - Tier 1 - CIHR Funded
  • 批准号:
    384890
  • 项目类别:
  • 资助金额:
    $101.99万
  • 财政年份:
    2017
  • 负责人:
    Zhen Mei
  • 依托单位:
An Anatomic and Genetic Dissection of Synapse Formation and Synapse Remodelling
  • 批准号:
    357854
  • 项目类别:
    Operating Grants
  • 资助金额:
    $52.39万
  • 财政年份:
    2016
  • 负责人:
    Zhen Mei
  • 依托单位:
Which Direction to Go? An Optogenetic Interrogation of the C. elegans Motor Circuit
Regulation of Axon Migration and Synapse Patterning during the Nervous System Development
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