Dystonin - a cytoskeletal linker protein critical for neuronal function

Dystonin - 一种对神经元功能至关重要的细胞骨架连接蛋白

• 批准号: 266669
• 负责人: Kothary Rashmi K
• 金额: $ 53.51万
• 依托单位: Ottawa Hospital Research Institute
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2012
• 资助国家: 加拿大
• 起止时间: 2012-09-01 至 2017-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=266669&lang=en
• 关键词: Autophagy; Cytoskeletal Linker Proteins; Established And Primary Cell Culture Models; Intracellular Trafficking; Microtubule Dynamics; Mouse Models; Neurodegenerative Diseases; Neuronal Integrity; Transgenic Mice

Defects in cytoskeletal proteins have a primary role in many neurodegenerative diseases. In working towards therapies for these diseases, it is important to understand the basic context in which the conditions occur. Implicit in this is an understanding o

细胞骨架蛋白的缺陷在许多神经退行性疾病中起主要作用。在致力于治疗 对于这些疾病，重要的是要了解这些疾病发生的基本背景。这里面隐含着一个 理解O