Neural and hormonal control of visceral systems

内脏系统的神经和激素控制

• 批准号: 155416-2009
• 负责人: Lange, Angela
• 金额: $ 3.5万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2013
• 资助国家: 加拿大
• 起止时间: 2013-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=522619
• 关键词: Neural; hormonal; control; visceral; systems

My overall research interests lie within the field of insect neurobiology/physiology. I am interested in the means by which the reproductive system, and indeed, other insect visceral muscle systems, are regulated and integrated by both neural and hormonal signals. To this end my research laboratory has developed model systems in which we have identified the motor and modulatory input onto tissues associated with the reproductive systems of the agricultural pest, Locusta migratoria, and in the medically-important vector of Chagas' disease, Rhodnius prolixus. Neuroactive substances have been identified associated with the innervation of the reproductive system and have also been shown to be associated with the digestive and the circulatory system. There is an integral link between these systems since the nutritional state of the insect influences the reproductive state, and the heart circulates nutrient and neurohormones throughout the insect.

我的总体研究兴趣在于昆虫神经生物学/生理学领域。 我感兴趣的是生殖系统以及其他昆虫内脏肌肉系统是如何被神经和激素信号调节和整合的。 为此，我的研究实验室开发了模型系统，其中我们已经确定了与农业害虫飞蝗生殖系统相关的组织的运动和调节输入，以及在医学上重要的恰加斯病载体Rhodnius prolixus中。 神经活性物质已被确定与生殖系统的神经支配有关，也已被证明与消化和循环系统有关。这些系统之间存在着不可分割的联系，因为昆虫的营养状态影响着生殖状态，而心脏则使营养和神经激素在整个昆虫体内循环。