Domestication and transduplication: The role of transposable elements in genome evolution

驯化和转复制：转座元件在基因组进化中的作用

• 批准号: 183960-2010
• 负责人: Bureau, Thomas
• 金额: $ 2.91万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2013
• 资助国家: 加拿大
• 起止时间: 2013-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=522997
• 关键词: Domestication; transduplication; role; transposable; elements

The genome of higher organisms is commonly thought to be consisting of genes. But far outnumbering genes are entities called transposable elements or transposons. They are often characterized as molecular parasites, selfish DNA or even as junk DNA. They differ from genes in that they can move within the genome frequently leading to mutations and an overall reduction in the fitness of the organism. Despite this "evil" side of transposons, they appear to also have a "good" side.

高等生物的基因组通常被认为是由基因组成的。但数量远远超过基因的是被称为转座因子或转座子的实体。它们通常被描述为分子寄生虫，自私的DNA，甚至是垃圾DNA。它们与基因的不同之处在于，它们可以在基因组内移动，经常导致突变和生物体适应性的整体降低。尽管转座子有“邪恶”的一面，但它们似乎也有“好”的一面。