Signalling mechanisms in cell survival and cell growth

细胞存活和细胞生长的信号机制

• 批准号: 227932-2009
• 负责人: Staveley, Brian
• 金额: $ 3.64万
• 依托单位: Memorial University of Newfoundland
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2013
• 资助国家: 加拿大
• 起止时间: 2013-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=524153
• 关键词: Signalling; mechanisms; cell; survival; growth

The control of life and death is as crucial as any question in biology. The survival and growth of cells are controlled by mechanisms that interpret signals from both inside and outside the cell to alter its activity. Over recent years, the processes that control cell death have become very well understood. More recently, the cellular functions that help cells live and grow are being recognised as interdependent. In our laboratory, we study the common fruit fly, the genes of which are far more similar to humans than we once thought. It is an ideal model organism to study this aspect of cell biology.

对生与死的控制和生物学中的任何问题一样重要。细胞的存活和生长是由解释来自细胞内外的信号以改变其活性的机制控制的。 近年来，控制细胞死亡的过程已经得到了很好的理解。 最近，帮助细胞生存和生长的细胞功能被认为是相互依赖的。 在我们的实验室里，我们研究的是普通的果蝇，它们的基因与人类的相似程度远远超过我们曾经的想象。 它是研究这方面细胞生物学的理想模式生物。