Quantifying the dynamics of protein function at the atomic level using NMR and calorimetry
Quantifying the dynamics of protein function at the atomic level using NMR and calorimetry
批准号:
327028-2009
负责人:
Mittermaier, Anthony
金额:
$3.64万
依托单位:
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2013
资助国家:
加拿大
项目状态:
已结题
起止时间:
2013-01-01 至 2014-12-31
中文摘要
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英文摘要
Proteins are central players in an enormous variety of cellular processes, thus understanding how they function is critical to understanding the molecular basis of life. Proteins are highly flexible molecules, and there is growing evidence that their internal dynamics play an essential, but still poorly understood, role in their biological activities. We will use three complementary biophysical techniques to relate the internal motions of protein molecules to their function: Nuclear magnetic resonance (NMR), isothermal titration calorimetry (ITC) and differential scanning calorimetry (DSC).
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批准号:RGPIN-2022-03242
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项目类别:Discovery Grants Program - Individual
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资助金额:$4.52万
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Binding Mechanisms and Conformational Equilibria in Biomacromolecular Interactions
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批准号:RGPIN-2014-05776
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.93万
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财政年份:2020
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依托单位:
Binding Mechanisms and Conformational Equilibria in Biomacromolecular Interactions
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批准号:RGPIN-2014-05776
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.93万
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财政年份:2019
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负责人:Mittermaier, Anthony
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依托单位:
Binding Mechanisms and Conformational Equilibria in Biomacromolecular Interactions
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批准号:RGPIN-2014-05776
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.93万
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财政年份:2018
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负责人:Mittermaier, Anthony
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依托单位:
Binding Mechanisms and Conformational Equilibria in Biomacromolecular Interactions
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批准号:RGPIN-2014-05776
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.93万
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财政年份:2017
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负责人:Mittermaier, Anthony
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依托单位:
Binding Mechanisms and Conformational Equilibria in Biomacromolecular Interactions
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批准号:RGPIN-2014-05776
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.93万
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财政年份:2016
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负责人:Mittermaier, Anthony
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依托单位:
Binding Mechanisms and Conformational Equilibria in Biomacromolecular Interactions
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批准号:RGPIN-2014-05776
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.93万
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财政年份:2015
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负责人:Mittermaier, Anthony
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依托单位:
Binding Mechanisms and Conformational Equilibria in Biomacromolecular Interactions
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批准号:RGPIN-2014-05776
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.93万
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财政年份:2014
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负责人:Mittermaier, Anthony
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依托单位:
Quantifying the dynamics of protein function at the atomic level using NMR and calorimetry
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批准号:327028-2009
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$3.64万
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财政年份:2012
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负责人:Mittermaier, Anthony
-
依托单位:
Quantifying the dynamics of protein function at the atomic level using NMR and calorimetry
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批准号:327028-2009
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项目类别:Discovery Grants Program - Individual
-
资助金额:$3.64万
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财政年份:2011
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负责人:Mittermaier, Anthony
-
依托单位:
Quantifying the dynamics of protein function at the atomic level using NMR and calorimetry
-
批准号:327028-2009
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项目类别:Discovery Grants Program - Individual
-
资助金额:$3.64万
-
财政年份:2010
-
负责人:Mittermaier, Anthony
-
依托单位:
Quantifying the dynamics of protein function at the atomic level using NMR and calorimetry
-
批准号:327028-2009
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$3.64万
-
财政年份:2009
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负责人:Mittermaier, Anthony
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依托单位:
Engineering protein dynamics and function using NMR, mutagenesis, and calorimetry
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批准号:327028-2006
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.78万
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财政年份:2008
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负责人:Mittermaier, Anthony
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依托单位:
High field NMR spectrometer for chemical biology research
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批准号:360010-2008
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项目类别:Research Tools and Instruments - Category 1 (<$150,000)
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资助金额:$10.93万
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财政年份:2007
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负责人:Mittermaier, Anthony
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依托单位:
Engineering protein dynamics and function using NMR, mutagenesis, and calorimetry
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批准号:327028-2006
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项目类别:Discovery Grants Program - Individual
-
资助金额:$2.78万
-
财政年份:2007
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负责人:Mittermaier, Anthony
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依托单位:
Engineering protein dynamics and function using NMR, mutagenesis, and calorimetry
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批准号:327028-2006
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.78万
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财政年份:2006
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负责人:Mittermaier, Anthony
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依托单位:
Differential scanning calorimeter for studying the thermodynamics of protein folding
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批准号:330931-2006
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项目类别:Research Tools and Instruments - Category 1 (<$150,000)
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资助金额:$7.46万
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财政年份:2005
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负责人:Mittermaier, Anthony
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依托单位:
Studying protein dynamics by computer simulation: incorporation of NMR data
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批准号:267865-2003
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项目类别:Postdoctoral Fellowships
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资助金额:$0.49万
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财政年份:2005
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负责人:Mittermaier, Anthony
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依托单位:
Studying protein dynamics by computer simulation: incorporation of NMR data
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批准号:267865-2003
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项目类别:Postdoctoral Fellowships
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资助金额:$2.91万
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财政年份:2004
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负责人:Mittermaier, Anthony
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依托单位:
国内基金
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