The role of longin-SNAREs in proteins sorting and membrane fusion

点击翻译按钮获取中文摘要

Exocytosis and membrane fusion are mechanisms used by all cells to maintain their survival and perform their unique functions. This process involves the transport of intracellular vesicles to the cell periphery where they dock and undergo membrane fusion, resulting in the release of their contents extracellularly. For example, white blood cells can attack and degrade invading pathogens by releasing intracellular enzymes and chemical mediators of inflammation. Since these enzymes and chemicals are toxic they are sequestered in intracellular packages called vesicles and only released by exocytosis and membrane fusion at the cell periphery when invading pathogens are sensed.