Kinase control of Bax-mediated neuronal apoptosis

Bax 介导的神经元凋亡的激酶控制

• 批准号: 283925
• 负责人: Ambacher Kristin K
• 金额: $ 5.1万
• 依托单位: University of Western Ontario
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2012
• 资助国家: 加拿大
• 起止时间: 2012-10-01 至 2014-10-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=283925&lang=en
• 关键词: Axotomy; Bcl-2 Family Proteins; Cerebellar Granule Neurons; Molecular Biology; Neuronal Apoptosis; Neurophysiology; Transcriptional Control; Trophic Factor Withdrawal

When cells are exposed to stress, they often undergo a process of programmed cell death called apoptosis. When this type of cell death occurs in brain cells it can contribute to neurodegenerative diseases, including Alzheimer's, Parkinson's and Huntingto

当细胞暴露于压力时，它们通常会经历一个称为凋亡的程序性细胞死亡过程。 当这种类型的细胞死亡发生在脑细胞中时，它可能导致神经退行性疾病，包括阿尔茨海默氏症，帕金森氏症和亨廷顿氏症