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The Role of the RasGTPase Superfamily Signaling in C.elegans

The Role of the RasGTPase Superfamily Signaling in C.elegans
RasGTPase 超家族信号传导在秀丽隐杆线虫中的作用
批准号:
342190-2013
负责人:
Kubiseski, Terrance
金额:
$2.19万
依托单位:
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2013
资助国家:
加拿大
项目状态:
已结题
起止时间:
2013-01-01 至 2014-12-31

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中文摘要
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英文摘要
The Ras-family of proteins plays crucial regulatory roles in biology by controlling cell growth and development. Inappropriate activity of this family of proteins is known to lead to human diseases and they play a fundamental role in cell biology. Although we have a good understanding of some simple functions of these proteins, some things we do not know are (i) how they are regulated, (ii) once they are switched on, what other proteins do they bind and (iii) how these proteins are altered to carry out their biological function.
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