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Leptin action in a gut-brain axis and involvement in the glucose-lowering effect of duodenal-jejunal bypass surgery

Leptin action in a gut-brain axis and involvement in the glucose-lowering effect of duodenal-jejunal bypass surgery
瘦素在肠脑轴中的作用以及参与十二指肠空肠绕道手术的降血糖作用
批准号：
274460
负责人：
Rasmussen Brittany A
金额：
$10.93万
依托单位：
University of Toronto
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2012
资助国家：
加拿大
项目状态：
已结题
起止时间：
2012-11-01 至 2015-11-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=274460&lang=en
关键词：
Adenovirus Diabetic Animal Model Gastric Bypass Surgery Glucose Metabolism Glucose Production Gut-Brain-Liver Axis Hormone Action Intestinal Signaling Leptin Pancreatic Glucose/Insulin Clamp

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Diabetes and obesity are characterized by a disruption in glucose homeostasis due partly to an elevation in hepatic glucose production. Thus, it is important to understand the mechanism(s) involved. The peptide hormone leptin has been shown to regulate gl
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