The Effect of Dietary n-3 Polyunsaturated Fatty Acids on Intestinal Mucosal Integrity in Inflammatory Bowel Disease

膳食 n-3 多不饱和脂肪酸对炎症性肠病肠粘膜完整性的影响

• 批准号: 184579
• 负责人: Ryz Natasha R
• 金额: $ 7.29万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2008
• 资助国家: 加拿大
• 起止时间: 2008-11-01 至 2010-11-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=184579&lang=en
• 关键词: Bacteria; Citrobacter Rodentium; Fluorescent In Situ Hybridization; Inflammatory Bowel Disease; Innate Immunity; Intestinal Epithelial Cells; Mucosal Integrity; N-3 Polyunsaturated Fatty Acids; Nutrition; Toll-Like Receptors

Inflammatory bowel disease (IBD) is thought to result from damage to the intestinal barrier, which allows bacteria or food components to leak across the intestine and interact with the immune system. Interestingly, dietary fat may play a role in the cause

炎症性肠病(IBD)被认为是肠道屏障受损的结果，肠道屏障允许细菌或食物成分通过肠道渗漏，并与免疫系统相互作用。有趣的是，饮食中的脂肪可能在病因中扮演了一个角色。