Modulation of Ca2+/Calmodulin-Dependent Protein Kinase Isoform II (CaMKII) Localization and Activity

Ca2/钙调蛋白依赖性蛋白激酶亚型 II (CaMKII) 定位和活性的调节

• 批准号: 279773
• 负责人: Paige Brian
• 金额: $ 1.27万
• 依托单位: University of Ottawa
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2013
• 资助国家: 加拿大
• 起止时间: 2013-02-01 至 2014-02-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=279773&lang=en
• 关键词: Arrhythmia; Bacterial Transformation; Calcium Binding Curve; Calcium Ion Channel; Cardiomyopathy; Cell Culture; Excitation-Contraction Coupling; Literature Review; Phosphorylation Assay; Western Blotting

For people with certain heart conditions, such as arrhythmias and heart failure, the amount of calcium in compartments within the human heart tends to be poorly controlled. It has been found that these poorly regulated calcium levels are linked to an ove

对于患有某些心脏疾病的人，如心律失常和心力衰竭，人体心脏内部隔室中的钙量往往控制不佳。研究发现，这些调节不佳的钙水平与卵巢癌有关。