Effects of cytokine deregulation caused by HIV-1 vs HIV-2 infection of antigen presenting cells on CD4 T-cell polarization and function

HIV-1 与 HIV-2 抗原呈递细胞感染引起的细胞因子失调对 CD4 T 细胞极化和功能的影响

• 批准号: 279750
• 负责人: Donahue Daniel A
• 金额: $ 10.93万
• 依托单位: Ecole Normale Suprieure de Lyon (France)
• 依托单位国家: 加拿大
• 项目类别: Fellowship Programs
• 财政年份: 2013
• 资助国家: 加拿大
• 起止时间: 2013-02-01 至 2016-02-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=279750&lang=en
• 关键词: Aids; Flow Cytometry; Hiv; Immunology; Macrophage; Pathogenesis; T-Cell

HIV-1 is the virus responsible for the worldwide AIDS outbreak. HIV-2 is closely related to HIV-1, but HIV-2 causes only a mild form of AIDS and is much less common than HIV-1. We are comparing how these two viruses infects cells of the immune system. We

HIV-1是导致全球艾滋病爆发的病毒。HIV-2与HIV-1密切相关，但HIV-2只会引起一种轻微的艾滋病，比HIV-1少见得多。我们正在比较这两种病毒是如何感染免疫系统细胞的。我们