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The identification of master regulatory genes (MRGs) whose altered expression and activation play a central role in the development of metastatic prostate cancer

The identification of master regulatory genes (MRGs) whose altered expression and activation play a central role in the development of metastatic prostate cancer
鉴定主调控基因（MRG），其表达和激活的改变在转移性前列腺癌的发展中发挥核心作用
批准号：
280826
负责人：
Choi Stephen Y
金额：
$1.27万
依托单位：
B.C. Cancer Research Centre (Vancouver)
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2013
资助国家：
加拿大
项目状态：
已结题
起止时间：
2013-02-01 至 2014-02-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=280826&lang=en
关键词：
Bioinformatics Master Regulator Metastasis Next-Generation Sequencing Prostate Cancer Therapeutic Targets Xenograft

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英文摘要
Background: Prostate cancer is the most frequently diagnosed cancer in North American men. While current therapies are able to cure prostate cancer if it is discovered at the early stages, therapies for late-stage prostate cancer (i.e. prostate cancer spr
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Targeting monocarboxylate transporter 4 (MCT4) for treatment of castration resistant prostate cancer (CRPC)
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