Characterization and functional analyses of incorporated HERV envelope proteins in placenta-derived exosomes

胎盘来源的外泌体中整合的 HERV 包膜蛋白的表征和功能分析

• 批准号: 281657
• 负责人: Barbeau Benoit
• 金额: $ 32.85万
• 依托单位: Universit du Qubec Montral
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2013
• 资助国家: 加拿大
• 起止时间: 2013-03-01 至 2017-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=281657&lang=en
• 关键词: Biomarkers; Cellular Binding; Envv And Envp(B); Exosomes; Human Endogenous Retroviruses; Human Trophoblasts; Immunosuppression; Placenta; Pre-Eclampsia; Syncytin-1 And Syncytin-2; Uptake And Fusion

Human endogenous Viruses (HERVs) are sequences having been conserved over millions of years in our genome and produce proteins originating from former viruses. Some of these proteins are important for the normal development of the placenta. Changes in the

人类内源性病毒(HERV)是在我们的基因组中保存了数百万年的序列，并产生来自以前病毒的蛋白质。其中一些蛋白质对胎盘的正常发育很重要。的变化