Detection of HIV-1 ASP and characterization of its modulation of viral replication through induced autophagy

HIV-1 ASP 的检测及其通过诱导自噬调节病毒复制的表征

• 批准号: 297518
• 负责人: Barbeau Benoit
• 金额: $ 7.29万
• 依托单位: Universit du Qubec Montral
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2013
• 资助国家: 加拿大
• 起止时间: 2013-09-01 至 2014-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=297518&lang=en
• 关键词: Antisense Protein; Antisense Transcription; Autophagy; Electron Microscopy; Elisa Detection; Hiv-1; Leukapheresis; Magnetic Bead-Based Cell Sorting; Monocytes And Macrophages; Multimerisation

Previous studies have suggested the existence of a new Human Immunodeficiency Virus type 1 (HIV-1) gene termed Antisense Protein (ASP). The proposed encoded protein has been difficult to detect in infected cells, and this has been a major source of conce

以前的研究表明存在一种新的人类免疫缺陷病毒1型（HIV-1）基因，称为反义蛋白（ASP）。 在被感染的细胞中很难检测到这种编码的蛋白质，这也是引起感染的主要原因。