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The development of safer oncolytic poxviruses dependent on cellular dNTP synthesis

The development of safer oncolytic poxviruses dependent on cellular dNTP synthesis
依赖细胞 dNTP 合成开发更安全的溶瘤痘病毒
批准号:
282191
负责人:
Evans David H
金额:
$54.53万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2013
资助国家:
加拿大
项目状态:
已结题
起止时间:
2013-03-01 至 2018-03-01

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中文摘要
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英文摘要
During the process of transformation, a cancer cell acquires many different mutations. However, these mutations can sometimes create an "Achilles heel" in that they often render cancer cells sensitive to virus infection. Oncolytic virus therapies try to e
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Poxvirus replication and recombination as drivers of genome evolution
  • 批准号:
    381571
  • 项目类别:
    Operating Grants
  • 资助金额:
    $61.3万
  • 财政年份:
    2018
  • 负责人:
    Evans David H
  • 依托单位:
Biochemical and genetic studies of the mechanism of poxvirus replication and recombination
  • 批准号:
    253292
  • 项目类别:
    Operating Grants
  • 资助金额:
    $42.4万
  • 财政年份:
    2012
  • 负责人:
    Evans David H
  • 依托单位:
海外基金