A study of ozonolysis reactions for lipid transformations by mass spectrometry

质谱法研究脂质转化的臭氧分解反应

• 批准号: 197273-2011
• 负责人: Curtis, Jonathan
• 金额: $ 1.82万
• 依托单位: University of Alberta
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2014
• 资助国家: 加拿大
• 起止时间: 2014-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=546195
• 关键词: study; ozonolysis; reactions; lipid; transformations

Ozonolysis involves the reaction of ozone with unsaturated organic compounds. It has been used as a method to determine double bond positions in natural products and lipids for more than half a century. Recently, the ozonolysis of lipids has been combined with electrospray mass spectrometry, thereby allowing direct observation of the ozonolysis products. Ozonolysis is also being developed as part of a process to convert the unsaturated fatty acids present in vegetable oils into compounds known as "polyols" which are used in the manufacture of polyurethanes. Polyols produced from renewable resources, such as canola oil, could replace some of the millions of tonnes of polyols produced by the petrochemical industry for making a wide range of materials including rigid and elastic foams, coatings, adhesives and plastics.

臭氧分解涉及臭氧与不饱和有机化合物的反应。 半个多世纪以来，它一直被用作测定天然产物和脂质中双键位置的方法。 最近，脂质的臭氧分解已经与电喷雾质谱法相结合，从而允许直接观察臭氧分解产物。 臭氧分解也被开发为将植物油中存在的不饱和脂肪酸转化为用于制造聚氨酯的称为“多元醇”的化合物的过程的一部分。 从可再生资源生产的多元醇，如菜籽油，可以取代石化工业生产的数百万吨多元醇中的一部分，用于制造各种材料，包括刚性和弹性泡沫，涂料，粘合剂和塑料。