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Regulation of UV Damage Repair by the ATR-mediated DNA Damage Checkpoint in Malignant Melanoma

Regulation of UV Damage Repair by the ATR-mediated DNA Damage Checkpoint in Malignant Melanoma
ATR 介导的 DNA 损伤检查点对恶性黑色素瘤中紫外线损伤修复的调节
批准号：
291385
负责人：
Drobetsky Elliot A
金额：
$26.56万
依托单位：
Centre de recherche de l'Hôpital Maisonneuve-Rosemont (Montral)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2013
资助国家：
加拿大
项目状态：
已结题
起止时间：
2013-09-01 至 2016-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=291385&lang=en
关键词：
Atr Kinase Cell Cycle Confocal Microscopy Dna Sequencing Flow Cytometry Genomic Instability Malignant Melanoma Nucleotide Excision Repair Q-Rt-Pcr

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Damage to our genes due to excessive exposure to solar UV rays is considered the major cause of malignant melanoma, a deadly form of skin cancer that occurs very frequently in young adults and is extremely difficult to treat. Fortunately, humans possess a
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