Characterization of a new "intracellular immunization" strategy restricting HIV-1 infection and inducing host immune response
Characterization of a new "intracellular immunization" strategy restricting HIV-1 infection and inducing host immune response
批准号:
297414
负责人:
Yao Xiao-Jian
金额:
$7.29万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2013
资助国家:
加拿大
项目状态:
已结题
起止时间:
2013-09-01 至 2014-09-01
中文摘要
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英文摘要
APOBEC3G (A3G), a deoxycytidine deaminase, is a powerful host antiviral factor that is able to restrict HIV infection by causing virus hypermutations. Moreover, A3G was also shown to act as an inducer of the adaptive immune response. However, during a wi
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