Advanced mathematical modelling and numerical simulation of blood flow: from the microscale to the macroscale

血流高级数学建模和数值模拟：从微观到宏观

• 批准号: 312542-2010
• 负责人: Owens, Robert
• 金额: $ 2.04万
• 依托单位: Université de Montréal
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2014
• 资助国家: 加拿大
• 起止时间: 2014-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=548785
• 关键词: Advanced; mathematical; modelling; numerical; simulation

In the proposed project we aim to build on our research achievements in the area of haemorheology over the past five years to provide a detailed rheological description of in vitro blood flows all the way from those in large diameter vessels (macroscale, continuum or micro-macro description) to those in the microvasculature (microscale, discrete modelling methods). We aim to be able to consistently describe flows in vessels of intermediate size (c. 100 microns in diameter) using either approach. We will continue our commitment to the experimental validation, wherever possible, of our quantitative predictions.

在拟议的项目中，我们的目标是在过去五年我们在血液流变学领域的研究成果的基础上，提供从大直径血管中的血液流动(宏观、连续或微观宏观描述)到微血管系统中的血液流动(微观尺度、离散建模方法)的详细流变学描述。我们的目标是能够一致地描述中等大小(直径约100微米)容器中的流动。只要有可能，我们将继续致力于对我们的定量预测进行实验验证。