The role of anti-homocitrullinated protein/peptide immune responses in Rheumatoid Arthritis

抗高瓜氨酸蛋白/肽免疫反应在类风湿性关节炎中的作用

• 批准号: 290522
• 负责人: Cairns Ewa
• 金额: $ 39.11万
• 依托单位: University of Western Ontario
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2013
• 资助国家: 加拿大
• 起止时间: 2013-09-01 至 2017-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=290522&lang=en
• 关键词: Anti-Citrullinated Protein/Peptide Antibodies (Acpa); Anti-Homocitrullinated Protein/Peptide Antibodies (Hcpa); Arthritis Animal Models; Autoimmune Disease; B Cells; Dr4 (Se) Transgenic Mice; Mhc Class Ii; Rheumatoid Arthritis (Ra); Shared Epitope (Se); T

It has been recent dogma that Rheumatoid Arthritis (RA), the most common inflammatory and crippling type of arthritis is characterized by the presence of a serum factor called anti-citrullinated protein/peptide antibody or ACPA. The presence of ACPA helps

最近的教条是风湿性关节炎（RA），最常见的炎性和致残性关节炎类型，其特征在于存在称为抗瓜氨酸化蛋白/肽抗体或ACPA的血清因子。ACPA的存在有助于