Arthritogenicity of the immune response to citrullinated antigens

对瓜氨酸抗原的免疫反应的致关节炎性

• 批准号: 196385
• 负责人: Cairns Ewa
• 金额: $ 7.29万
• 依托单位: University of Western Ontario
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2009
• 资助国家: 加拿大
• 起止时间: 2009-09-01 至 2010-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=196385&lang=en
• 关键词: Citrullinated Antigens; Hla-Drb1*0401 Transgenic Mice; Ra Patients; Rheumatoid Arthritis (Ra); T And B Cell Responses To Citrullinated Antigens

Rheumatoid Arthritis (RA) is a common, chronic and crippling disease that destroys cartilage and bone in the joints. The cause of RA is not known but it has been shown that two factors are frequently found in RA patients. One of these is a genetic factor

类风湿性关节炎(RA)是一种常见的慢性致残性疾病，破坏关节的软骨和骨骼。类风湿性关节炎的病因尚不清楚，但已有研究表明在类风湿性关节炎患者中经常发现两种因素。其中之一是遗传因素。