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The PrPC / PDK1 / TACE signaling axis at the cross-road of several aggregate-prone protein-associated neurodegenerative diseases

The PrPC / PDK1 / TACE signaling axis at the cross-road of several aggregate-prone protein-associated neurodegenerative diseases
PrPC / PDK1 / TACE 信号轴位于几种易聚集蛋白相关神经退行性疾病的十字路口
批准号:
314196
负责人:
Fon Edward A
金额:
$36.42万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2014
资助国家:
加拿大
项目状态:
已结题
起止时间:
2014-06-01 至 2017-06-01

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中文摘要
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英文摘要
The aims of the consortium are to decipher the molecular and cellular mechanisms of neurodegeneration induced by diverse aggregate-prone proteins found in AD, prion diseases, PD, ALS, FTD and SCA-1 in order to identify susceptibility factors and therapeut
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Canada Research Chair Tier 1
  • 批准号:
    392568
  • 项目类别:
  • 资助金额:
    $101.99万
  • 财政年份:
    2018
  • 负责人:
    Fon Edward A
  • 依托单位:
Function of Parkinson Disease Genes in Mitochondrial Quality Control
Cellular and Molecular Mechanisms of Neurodegeneration in Parkinson's Disease
Targeting Prion-like Propagation of Alpha-Synuclein Pathology in Parkinson's Disease
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