Multifunctional microplate readers for assays of cellular activity and molecular quantification

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It is well established that using an integrated approach is required to understand the complexity of biological organization. To achieve this, our six research groups study the signals and regulatory mechanisms involved in gene expression, the kinetics of protein activities, and cell physiology. We require laboratory equipment that can be shared between our collaborating research groups and used reliably for multiple different applications to advance our research programs and to continue to collaborate effectively with one another. Multifunctional microplate readers, one capable of culturing cells and measuring visible light absorbance, fluorescence, and luminescence (item 1) coupled with a microplate reader for measuring UV absorbance (item 2), will together provide a core platform for addressing many physiological, biochemical, and molecular questions. These indispensable tools will operate at maximum capacity for many years, supporting the research programs of six NSERC-funded researchers.